The Whites went head-to-head with the Owls in a crucial Championship clash.
After being held up by the opponents for around an hour, Harrison broke the deadlock in the 65th minute with a composed finish.
The 22-year-old netted past the goalkeeper with great poise.
The Manchester City loanee, once again, lived up to the expectation, as Leeds took a giant leap towards Premier League promotion.
Harrison has netted four goals and provided two assists in more than 30 games this season.
Marcelo Bielsa’s first season at Elland Road has been very productive, as his side are currently second in the Championship table, trailing Norwich City by four points.
Furthermore, their promotion-chasing rivals Sheffield United slipped up after a draw against Millwall on Saturday.
Pablo Hernandez and Patrick Bamford have been some of the key players for the Whites this season, rising to the occasion, whenever the team needed them the most.
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With only four games left to play, Leeds will be looking to avoid the playoff scenario and try to achieve automatic promotion to England’s top flight next season.