3. Mesut Ozil vs. Victor Wanyama
The Arsenal attacker was one of the players who had an off day against Chelsea, he was also shackled extremely well by a well-disciplined Chelsea team and that is exactly what Southampton would have to do to nullify his effect on the game.
The onus on keeping the German quiet in the game would fall on the capable Victor Wanyama. The Southampton midfielder might have had a slow start to the season but recent performances have shown that the 24-year-old Kenyan is back to doing what he does best and that is destroying the opposition.